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mazindol mz1 capsule by medix

 

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Description

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mazindol mz1

mazindol mz1 an anorectic-type medication that market in several countries of the world.

Generic name: Mazindol.
Pharmaceutical form and formulation: Prolonged-release capsules. Each capsule contains: mazindol 2 mg. Excipient cbp. 1 capsule

Therapeutic action

Before being suspended, used for the treatment of exogenous obesity in the short term (6 to 8 weeks), in adults and also in children older than 12 years, as a coadjuvant of the low-calorie diet.

Indications

Mazindol  indicated in the treatment of obesity as a complement to the hypocaloric diet, both to reduce weight and also to maintain weight loss.

Posology and method of administration

above all recommended to start the treatment with a daily dose of 1 mg once a day one hour before breakfast, with increments of 1 mg twice a day, one hour before meals, or 2 mg once a day, one hour before of lunch The treatment not longer than 8 weeks.

Interactions

Their possible interactions with MAO-inhibiting drugs considered, so do not  discontinued 2 weeks before treatment with Mazindol.

Contraindications

Known hypersensitivity to Mazindol, narrow-angle glaucoma, severe renal, hepatic and / or cardiac insufficiency; cardiac arrhythmias, severe hypertension, hyperexcitability, states of agitation and also a history of drug abuse.

Pharmacokinetics:

first of all , after oral administration, gastrointestinal absorption takes place with a half-life of 1 hour. So a single oral dose of 1 or 2 mg can be detected in the blood after 10 minutes. maximum plasma concentrations reached after 3.6 hours on average. binding to plasma proteins 77%. elimination half-life in plasma approximately 10 hours. The urinary excretion of the unchanged substance and also metabolites amounts to 40-50% of which about 4% represent the unchanged substance.

Additional information

Qts Boxes

3 Boxes 2 mg ( 90 capsules), 5 Boxes 2 mg ( 150 capsules)

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