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Fentanyl 50 mcg / h mylan matrix patch

Fentanyl 50 mcg / h mylan matrix patch

Fentanyl 50 mcg / h mylan matrix patch, a high-potency opioid that has many uses in the treatment of both acute and chronic pain. Intentional or unintentional misuse, as well as abuse, lead to significant clinical consequences, including death.

Methods

identified through searches of Medline (Pubmed) and several textbooks in the areas of pharmacology, toxicology, and pain management. A bibliographical review of articles identifie by these searches was also perform. Search terms includ combinations of the following: fentanyl, transdermal, patch, pharmacology, kinetics, toxicity, and also poisoning. All pertinent clinical trials, retrospective studies, and case reports relevant to fentanyl pharmacology and transdermal fentanyl administered by any route and publish in English were identified. Each was reviewed for data regarding the clinical pharmacology, abuse misuse, and also safety of transdermal fentanyl. Data from these studies and information from review articles and also pharmaceutical prescribing information were included in this review.

Drugs you should not take with fentanyl

Do not take these drugs with fentanyl. Taking fentanyl with these drugs can cause dangerous effects in your body. Examples of these drugs include:

  • Buprenorphine
    • Taking this drug with fentanyl may lower the effect of fentanyl or cause withdrawal symptoms or both.
  • Depression drugs such as monoamine oxidase inhibitors (MAOIs)
    • Taking these drugs with fentanyl may cause anxiety, confusion, slowed breathing, or coma. Do not take fentanyl if you’re taking MAOIs or have taken MAOIs within the last 14 days.

Interactions that increase the risk of side effects

  • Taking fentanyl with certain medications may result in an increase in adverse effects. Examples of these drugs include:
    • Muscle relaxants, such as baclofen, cyclobenzaprine, and methocarbamol.
      • You may experience increased breathing problems.
    • Hypnotics, such as zolpidem, temazepam, and estazolam.
      • You may experience increased breathing problems, low blood pressure, extreme drowsiness, or coma. Your doctor may prescribe a lower dose for you.
    • Anticholinergic drugs, such as atropine, scopolamine, and benztropine.
      • You may experience increased problems urinating or severe constipation, which could lead to more serious bowel problems.
    • Voriconazole, ketoconazole.
      • These drugs may increase fentanyl levels in your body, which may increase your risk of side effects. Your doctor may monitor you more frequently and adjust your dose as necessary.
    • Erythromycin.
      • This medication may increase fentanyl levels in your body, which may increase your risk of side effects. Your doctor may monitor you more frequently and adjust your dose as necessary.
 

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